You must pay attention to the possible sealing and caulking
negative side effects.
See:
Basics on Ventilation
Weatherstripping,
caulking and ventilation
Since caulking and weather-stripping limit indoor-outdoor air
circulation, sealing air leaks in homes without proper
ventilation, will also seal their indoor air pollutants and
sources of air pollution related with heaters and appliances
(those that use gas, fuel oil, propane, wood...).
In other words: in some cases air leaks and gaps may act as a
mean for supplying air to homes, acting as vent openings and
contributing to ventilation needs. In this case, sealing the
gaps and sources of air leaks will contribute to fix the energy
loss problem but will also worsen the indoor air quality.
If you think that it may happen with your home, contact your
local utility company, or a ventilation or energy professional,
before sealing your gaps and air leaks.
See:
Weather-stripping
Caulking
Basics on Ventilation
Sealing and backdrafts
Fixing air leaks – through caulking and weatherstripping - may
also contribute to an increased possibility of backdrafts.
Backdrafting is unusual but is dangerous and you should be aware
of its possibility.
Backdrafts happen when gas, fuel or wood combustion appliances
compete for air with exhaust fans. Exhaust fans may pull the
combustion gases back into the rooms and living space, creating
air pollution and potentially very dangerous situations.
See also:
Home Energy Audit Basics
Simple tests involving
insulation
Attic and basement insulation
audit
Air leaks sources
Simple tests to identify home air
leaks
Professional
Thermographic inspections
Blower door test
Audits involving ductwork,
lighting and appliances
Professional home audits
Home
Energy Audit Software
Home
Energy Auditors: hiring and location
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Energy-Savings Home Page